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Case Report
Morgagni–Stewart–Morel syndrome: A new case
1 (Dr). Endocrinology Diabetes and Metabolic Diseases Department, Avicenna Military Hospital, Marrakesh, Morocco
2 (Pr). Endocrinology Diabetes and Metabolic Diseases Department, Avicenna Military Hospital, Marrakesh, Morocco
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Lahoussaine Abainou
(Dr). Endocrinology Diabetes and Metabolic Diseases Department, Avicenna Military Hospital, Marrakesh,
Morocco
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Article ID: 100070Z06LA2019
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Abainou L, El Jadi H, El Hadri S, Baizri H. Morgagni–Stewart–Morel syndrome: A new case. Case Rep Int 2019;8:100070Z06LA2019.ABSTRACT
Introduction: Morgagni–Stewart–Morel (MSM) syndrome is defined as the presence of hyperostosis frontalis interna (HFI) associated with metabolic, endocrine, and neuropsychiatric disorders. Here, we present an MSM syndrome case involving a woman with symptoms of depression and infertility.
Case Report: A 38-year-old woman admitted for inaugural diabetic ketosis and she reported a history of severe frontal headache of which she had suffered for several years associated to depression, obesity, and infertility. Axial cranial computed tomography (CT) scan showed bilateral thickening of the inner table of the frontal bone. Her endocrine dysfunctions and neuropsychiatric symptoms are interpreted as components of Morgagni–Stewart–Morel syndrome and may correlate with the severity of the frontal hyperostosis and the cortical atrophy.
Conclusion: We describe a case of MSM syndrome, presenting many of the clinical features described in the literature. The exact etiology of HFI and MSM syndrome remains unclear; the most interesting theories relate to estrogen dysfunction, obesity and leptin dysfunction, and genetics.
Keywords: Endocrine and neuropsychiatric disorders, Hyperostosis frontalis interna, Morgagni–Stewart–Morel syndrome
SUPPORTING INFORMATION
Author Contributions
Lahoussaine Abainou - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Hamza El Jadi - Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published
Sanae El Hadri - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Hicham Baizri - Substantial contributions to conception and design, Analysis of data, Drafting the article, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2019 Lahoussaine Abainou et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
