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Case Report
Lady Windermere syndrome: Reality or myth?
1 Resident Physician, Internal Medicine, Piedmont Athens Regional Medical Center, Athens, GA, USA
2 Residnt Physician, Internal Medicine, Piedmont Athens Regional Medical Center, Athens, GA, USA
3 Assistant Professor, Pulmonary and Critical Care, AU/UGA Medical Partnership, Athens Pulmonary and Sleep Medicine, Athens, GA, USA
Address correspondence to:
Prakash Adhikari
MD, 2400 Summerbrook Cir, Unit 2421, Athens, GA 30606,
USA
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Article ID: 100105Z06PA2022
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How to cite this article
Adhikari P, DaSilva R, Madala N, Fox N. Lady Windermere syndrome: Reality or myth? Case Rep Int 2022;11:100105Z06PA2022.ABSTRACT
Introduction: Mycobacterium avium complex (MAC) is a saprophytic bacterium which can cause pulmonary infection in patients with immunocompromised and structural lung disease. Infection in elderly, non-smoker and healthy women affecting right middle lobe is often referred as Lady Windermere syndrome.
Case Report: We present a case of an 80-year-old woman who presented with progressive worsening shortness of breath and cough and was found to have MAC infection. It is believed that voluntary cough suppression is a possible cause for the colonization and infection by MAC but our patient did not have this habit. Our patient chose not to get treated and she did relatively well without treatment.
Conclusion: Mycobacterium avium complex infection can occur in non-smoker with underlying lung conditions. There are guidelines for management of MAC pulmonary infection with multiple antibiotics and prolonged course and shared decision is recommended prior to initiation of the treatment.
Keywords: Bronchial disease, Bronchiectasis, Mycobacterium avium complex, Mycobacterium infection nontuberculous
SUPPORTING INFORMATION
Author Contributions
Prakash Adhikari - Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Rafael DaSilva - Acquisition of data, Drafting the article, Final approval of the version to be published
Nikhil Madala - Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Nik Fox - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2022 Prakash Adhikari et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
