A case of unilateral absent vas identified during vasectomy

Unilateral absence of the vas deferens is an uncommon congenital anomaly occurring in 0.5–1% of males [1],[2],[3] and accounts for 1–2% of male infertility [4]. It is fairly uncommon to encounter unilateral absent vas in a fertile male and in our literature review we discovered two other case reports describing the same [2],[5].

Here we present a case of a fertile male who underwent elective vasectomy and was identified to have unilateral absent vas deferens. We are presenting this case as a reminder of this anatomical variant and to share our experience with proceeding in such a situation, given vasectomy is a fairly routine low risk procedure that is more frequently being performed in the office under a local anesthetic.

A healthy 33-year-old male presented for elective vasectomy. He had fathered three children and had never been previously investigated for subfertility. His children were not known to suffer any illness.

The patient elected to have the vasectomy under a general anesthetic. The vas deferens on the right hand side was isolated following palpation and routine vasectomy was carried out without complication. On the left side, no definite vas deferens was palpable. An incision was made over the palpable cord structures, and a vas deferens was not identified on exploration the spermatic cord, the incision was then elongated, and the testis was explored in an attempt to find the vas deferens at its origin. A thorough examination of the testicle, testicular vessels, and epididymis revealed an absent vas deferens on the left. The testicle was returned to the left hemiscrotum and the operation completed.

The patient was informed of his diagnosis. A thorough family history revealed no cystic fibrosis and the patient declined genetic testing. An ultrasound scan was not performed.

The patient was reviewed in clinic in six weeks. He had recovered well from his operation and had two negative sperm samples and vasectomy was considered successful.

Congenital absence of vas deferens was first identified on autopsy in the 1700s and in 1870 it was described, by Reveredin, to be associated with multiple other congenital renal anomalies [6] as well as have an association with cystic fibrosis [4].

A review of published case reports demonstrate that a majority of these are identified during inguinal hernia repair in children, orchidopexy, or investigation for infertility in the male patient. Unilateral absent vas in the fertile male is rare, it has been described in the literature in two other case reports [2],[5]. In the case reported by Saitz and Thomas, the examination of the vas deferens was difficult prevasectomy and hence the decision was made for the patient to have their procedure under a general anesthetic, where unilateral absent vas was discovered, whereas in the case described by Khan and Novell, the patient underwent a vasectomy under local anesthesia and as the vas deferens was difficult to palpate intraoperatively the patient underwent a repeat procedure under a general anesthetic to confirm the absence of the vas deferens. Like our patient, both of these men were fertile and otherwise healthy, booked for elective vasectomy.

Unilateral absent vas deferens is an important anatomical variant that surgeons performing vasectomy should be aware of. Using our experience, and that from the two cases published in the literature, the authors recommend clinical examination when patients are booked in for vasectomy, and if there is difficulty palpating the vas deferens, the procedure should be carried out under a general anesthetic. Intraoperatively, if a vas is not identified the authors recommend exploration of the hemiscrotum to confirm absent vas deferens. Routine follow-up with semen analysis in 4–6 weeks, with barrier contraception use in the interim is recommended as is routine postvasectomy care to confirm sterility.

If the same situation is encountered during a vasectomy carried out under a local anesthetic, the cord structures should be explored as tolerated by the patient without delivery of the testis. If the vas is not identified, postoperative ultrasound scan should be performed to delineate scrotal anatomy and identify the vas, an abdominal ultrasound can also be performed at the same time as, if discovered, a renal anomaly would strengthen the diagnosis of a unilateral absent vas. If routine confirms sterility, the diagnosis of unilateral absent vas can be made. However, if there continues to be spermatozoa on the semen analysis, the patient can be given the option of scrotal exploration under a general anesthetic to identify the vas and complete vasectomy.

The authors did not feel that it was mandatory to perform a genetic test looking for cystic fibrosis in an otherwise healthy male who had completed his family and had healthy children. Many case reports and literature allude to the correlation between unilateral absent vas and unilateral renal agenesis. In our patient we did not perform one due to the reasons mentioned, but we would still recommend an ultrasound of the renal tract to the readers for completion as it is a simple and low risk test to perform [7].

As more of these cases are discovered, it would be interesting to see the success rate of vasectomies performed in patients found to have a unilateral absent vas intraoperatively.

Unilateral absent vas deferens is a rare finding in a fertile male. It is an important congenital anomaly to be aware of as a general surgeon performing elective vasectomy. If unilateral absent vas deferens is suspected on clinical exam prior to vasectomy, patients should undergo the procedure under a general anesthetic for scrotal exploration and confirmation of diagnosis.